Study on the Identification of Samples Mistyped as O Phenotype and the Strategy of Safe Blood Transfusion / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 910-916, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-880168
ABSTRACT
OBJECTIVE@#To investigate the indentification method of samples mistyped as O phenotype and to explore the precision transfusion strategy.@*METHODS@#The blood samples from donors and patients admitted in our center from 2018 to 2019 was collected. The samples with O phenotype suspected subtypes were further determined by tube test, adsorption-elution test, etc. Molecular testing was used to sequence the related blood type genes of the subjects.@*RESULTS@#Among 14 subjects misjudged as O, 11 different genotypes were identified, in which 3 blood donors were Ael02/O02, Bel03/O02, and one para-Bombay with B101/O02 (FUT1 h3h3; FUT2 Se@*CONCLUSION@#The phenotypes of Ael, Bel, Aw and para-Bombay subtypes are easily misjudged as type O. Molecular technology is helpful to identify the genotype of subtypes, and the corresponding transfusion strategies could be reasonably performed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Blood Transfusion
/
ABO Blood-Group System
/
Alleles
/
Fucosyltransferases
/
Genotype
Type of study:
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2021
Type:
Article
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