Kinetics of Infiltrating CD3 / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 931-936, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-880171
ABSTRACT
OBJECTIVE@#To explore the kinetics of infiltrated T cell in murine acute graft-versus-host disease (aGVHD) target organs after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and its relationship with tissue pathological damage and aGVHD progress.@*METHODS@#Male C57BL/6 (H-2K@*RESULTS@#Compared with BMT group, the number of infiltrated T cells in aGVHD target organs including liver, lung and gut increased since day 7 in BMT+T group (P<0.05). On day 14, 28, 40 and 47 after transplantation, more infiltrated CD3@*CONCLUSION@#Pathological damage of aGVHD target organs is induced by CD3
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Transplantation, Homologous
/
Kinetics
/
T-Lymphocytes
/
Bone Marrow Transplantation
/
Graft vs Host Disease
/
Mice, Inbred BALB C
/
Mice, Inbred C57BL
Limits:
Animals
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2021
Type:
Article
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