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Correlation of Mycoplasma genitalium infection with semen parameters and sperm DNA integrity in male infertility patients / 中华男科学杂志
National Journal of Andrology ; (12): 900-905, 2020.
Article in Chinese | WPRIM | ID: wpr-880289
ABSTRACT
Objective@#To analyze the relationship of Mycoplasma genitalium (MG) infection with routine semen parameters and sperm DNA integrity in male infertility patients.@*METHODS@#Totally, 114 semen samples, 34 MG-positive and 80 MG-negative, were collected from male infertility patients and subjected to routine semen analysis with the computer-assisted sperm analysis system, Papanicolaou staining for observation of sperm morphology, and sperm chromatin diffusion (SCD) test for detection of sperm DNA integrity. Semen parameters and DNA integrity were compared between the MG-positive and MG-negative groups with SPSS 21.0 statistical software and the relationship between the semen parameters and DNA integrity analyzed by Pearson correlation analysis.@*RESULTS@#The MG-positive samples, compared with the MG-negative ones, showed significantly decreased semen volume ([2.87 ± 0.37] vs [3.86 ± 0.43] ml, P 0.05).@*CONCLUSIONS@#MG infection may be an important factor affecting sperm quality in male infertility patients. Active prevention and treatment of MG infection can help prevent male infertility.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Semen / Sperm Count / Sperm Motility / Spermatozoa / Mycoplasma genitalium / DNA Fragmentation / Semen Analysis / Infertility, Male / Mycoplasma Infections Limits: Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Semen / Sperm Count / Sperm Motility / Spermatozoa / Mycoplasma genitalium / DNA Fragmentation / Semen Analysis / Infertility, Male / Mycoplasma Infections Limits: Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2020 Type: Article