Resveratrol inhibits Ca

Mikio MARUMO; Kazumi EKAWA; Ichiro WAKABAYASHI

Mikio MARUMO; Kazumi EKAWA; Ichiro WAKABAYASHI.

Environmental Health and Preventive Medicine ; : 70-70, 2020.

Article in English | WPRIM | ID: wpr-880306

ABSTRACT

ABSTRACT

BACKGROUND@#Resveratrol has been shown to inhibit platelet aggregation. However, the mechanism for this action of resveratrol remains to be clarified. The purpose of this study was to elucidate the Ca@*METHODS@#Ca@*RESULTS@#Thapsigargin-induced Ca@*CONCLUSIONS@#The results suggest that resveratrol inhibits thrombin-induced platelet aggregation through decreasing Ca

Subject(s)

Humans; Antioxidants/administration & dosage; Calcium/physiology; Platelet Aggregation/drug effects; Platelet Aggregation Inhibitors/pharmacology; Resveratrol/pharmacology; Signal Transduction/drug effects

Ca2+channels; Inositol trisphosphate; Platelet aggregation; Resveratrol; Store-operated Ca2+influx

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Platelet Aggregation Inhibitors / Signal Transduction / Platelet Aggregation / Calcium / Resveratrol / Antioxidants Limits: Humans Language: English Journal: Environmental Health and Preventive Medicine Year: 2020 Type: Article

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