Research progress in nervous system damage caused by SARS / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1247-1254, 2020.
Article
in English
| WPRIM
| ID: wpr-880593
ABSTRACT
The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major outbreak in the world. SARS-CoV-2 infection can not only involve in the respiratory system, but also cause severe nervous system damage. Studies have shown that SRAS-CoV-2 can invade the nervous system through hematogenous and transneuronal pathways, and may cause nervous system damage in patients with COVID-19 by inhibiting cellular immunity, hypoxemia, inflammation, inducing neuronal degeneration and apoptosis, and angiotensin converting enzyme 2 (ACE2) mechanism. It can lead to intracranial infection, toxic encephalopathy, acute cerebrovascular disease, muscle damage, peripheral nervous system injury, acute myelitis, demyelination disease or other nervous system diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia, Viral
/
Research
/
Coronavirus Infections
/
Peptidyl-Dipeptidase A
/
Pandemics
/
Betacoronavirus
/
SARS-CoV-2
/
COVID-19
Limits:
Humans
Language:
English
Journal:
Journal of Central South University(Medical Sciences)
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS