Effect of exosome / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 183-188, 2021.
Article
in English
| WPRIM
| ID: wpr-880641
ABSTRACT
Traumatic brain injury (TBI) is a main cause of death and disability worldwide, posing a serious threat to public health. But currently, the diagnosis and treatments for TBI are still very limited. Exosomes are a group of extracellular vesicles and participate in multiple physiological processes including intercellular communication and substance transport. Non-coding RNAs (ncRNA) are of great abundancy as cargo of exosomes. Previous studies have shown that ncRNAs are involved in several pathophysiological processes of TBI. However, the concrete mechanisms involved in the effects induced by exosome-derived ncRNA remain largely unknown. As an important component of exosomes, ncRNA is of great significance for diagnosis, precise treatment, response evaluation, prognosis prediction, and complication management after TBI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cell Communication
/
RNA, Untranslated
/
Exosomes
/
Extracellular Vesicles
/
Brain Injuries, Traumatic
Limits:
Humans
Language:
English
Journal:
Journal of Central South University(Medical Sciences)
Year:
2021
Type:
Article
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