Your browser doesn't support javascript.
loading
Mechanical heart valve thrombosis during pregnancy under non / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 207-211, 2021.
Article in English | WPRIM | ID: wpr-880645
ABSTRACT
Anticoagulation drugs should be used for patients with mechanical heart valve (MHV) in case of potential risk of thrombosis. Pregnant women with MHV have to change therapies due to teratogenic effect of some anti-coagulation drugs. European Society of Cardiology clinical guidelines for the management of cardiovascular diseases during pregnancy gives specific suggestions for anticoagulation therapy.We have treated 2 patients with mechanical heart valve thrombosis (MVT) during pregnancy One received low molecular weight heparin (LMWH) throughout the pregnancy and developed MVT at the third trimester of pregnancy; one developed MVT at the first trimester when replacing vitamin K antagonists (VKA) with LMWH. These patients raised secondary reflection on the balance between clinical guideline and personalized medicine. During LMWH therapy, we should dynamically monitor patients' anti-activated factor X (anti-Xa) level to evaluate coagulation function during pregnancy. When a pregnant woman with MHV develops symptoms of acute heart failure, stuck mechanical valve should be paid attention to and surgery should be promptly performed if necessary.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pregnancy Complications, Cardiovascular / Thrombosis / Heart Valve Prosthesis / Heparin, Low-Molecular-Weight / Heart Valves / Anticoagulants Type of study: Practice guideline Limits: Female / Humans / Pregnancy Language: English Journal: Journal of Central South University(Medical Sciences) Year: 2021 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pregnancy Complications, Cardiovascular / Thrombosis / Heart Valve Prosthesis / Heparin, Low-Molecular-Weight / Heart Valves / Anticoagulants Type of study: Practice guideline Limits: Female / Humans / Pregnancy Language: English Journal: Journal of Central South University(Medical Sciences) Year: 2021 Type: Article