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Correlation of type 2 diabetes and impaired glucose regulation with chronic kidney disease in middle-aged and elderly individuals / 南方医科大学学报
Journal of Southern Medical University ; (12): 1457-1464, 2020.
Article in Chinese | WPRIM | ID: wpr-880774
ABSTRACT
OBJECTIVE@#To explore the correlation of different glucose metabolism statues with chronic kidney disease (CKD) in middle-aged and elderly individuals in Lanzhou.@*METHODS@#Based on the baseline data of REACTION Study in Lanzhou area, we randomly sampled 10 038 residents aged 40-75 years in 3 communities in Lanzhou, who were classified into normal glucose tolerance (NGT), impaired glucose regulation (IGR) and diabetes groups. The estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (ACR) were used to assess the renal function and albuminuria, respectively. Binary logistic regression was performed to analyze the contribution of the risk factors to CKD. Polynominal regression was used to determine the trends of eGFR with the increment of ACR.@*RESULTS@#Among all the participants, the prevalences of albuminuria, CKD and renal insufficiency (RI) were 26.2%, 27.4% and 2.5%, respectively. The prevalence of albuminuria, CKD and RI were significantly higher in the diabetes group than in IGR and NGT groups (@*CONCLUSIONS@#Diabetes mellitus is a significant risk factor for albuminuria and RI, while IGR is not. Screening for albuminuria and eGFR is highly recommended for individuals with diabetes, hypertension, and obesity, especially in women and the elderly population.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prevalence / Risk Factors / Diabetes Mellitus, Type 2 / Albuminuria / Renal Insufficiency, Chronic / Glomerular Filtration Rate / Glucose Type of study: Etiology study / Prevalence study / Risk factors Limits: Adult / Aged / Female / Humans Language: Chinese Journal: Journal of Southern Medical University Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prevalence / Risk Factors / Diabetes Mellitus, Type 2 / Albuminuria / Renal Insufficiency, Chronic / Glomerular Filtration Rate / Glucose Type of study: Etiology study / Prevalence study / Risk factors Limits: Adult / Aged / Female / Humans Language: Chinese Journal: Journal of Southern Medical University Year: 2020 Type: Article