Electroacupuncture protects septic rats from acute lung injury through the JAK1/STAT3 pathway / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1662-1667, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-880797
ABSTRACT
OBJECTIVE@#To explore the protective effect of electroacupuncture against acute lung injury (ALI) in septic rats and explore the mechanism.@*METHODS@#Sixty male SD rats were randomly divided into cecal ligation and puncture (CLP)-induced sepsis group (@*RESULTS@#Compared with those in the sham operation group, the rats in ALI group showed obvious lung pathologies with significantly increased lung W/D ratio (@*CONCLUSIONS@#Electroacupuncture can inhibit the release of inflammatory mediators and cell apoptosis via the JAK1/STAT3 pathway to reduce lung injuries in septic rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Electroacupuncture
/
Tumor Necrosis Factor-alpha
/
Rats, Sprague-Dawley
/
Sepsis
/
Acute Lung Injury
/
Lung
Limits:
Animals
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2020
Type:
Article
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