Progress in systemic therapy for triple-negative breast cancer / 医学前沿
Frontiers of Medicine
;
(4): 1-10, 2021.
Article
in English
| WPRIM
| ID: wpr-880946
ABSTRACT
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with a heterogeneous genetic profile. Chemotherapy exhibits substantial activity in a small subset of these patients. Drug resistance is inevitable. Major progress has been made in the genetic analysis of TNBC to identify novel targets and increase the precision of therapeutic intervention. Such progress has translated into major advances in treatment strategies, including modified chemotherapy approaches, immune checkpoint inhibitors, and targeted therapeutic drugs. All of these strategies have been evaluated in clinical trials. Nevertheless, patient selection remains a considerable challenge in clinical practice.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Molecular Targeted Therapy
/
Triple Negative Breast Neoplasms
/
Immunotherapy
Limits:
Humans
Language:
English
Journal:
Frontiers of Medicine
Year:
2021
Type:
Article
Similar
MEDLINE
...
LILACS
LIS