Study on the secondary metabolites of grasshopper-derived fungi Arthrinium sp. NF2410 / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 957-960, 2020.
Article
in English
| WPRIM
| ID: wpr-881042
ABSTRACT
Two new 2-carboxymethyl-3-hexyl-maleic anhydride derivatives, arthrianhydride A (1) and B (2), along with three known compounds 3-5, were isolated from the fermentation broth of a grasshopper-associated fungus Arthrinium sp. NF2410. The structures of new compounds 1 and 2 were determined based on the analysis of the HR-ESI-MS and NMR spectroscopic data. Furthermore, compounds 1 and 2 were evaluated on inhibitory activity against the enzyme SHP2 and both of them showed moderate inhibitory activity against SHP2.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biological Products
/
Molecular Structure
/
Enzyme Inhibitors
/
Protein Tyrosine Phosphatase, Non-Receptor Type 11
/
Secondary Metabolism
/
Fungi
/
Grasshoppers
/
Anhydrides
Limits:
Animals
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2020
Type:
Article
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