Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for

Tingting JIANG; Guan WANG; Yao LIU; Lu FENG; Meng WANG; Jie LIU; Yi CHEN; Liang OUYANG

Tingting JIANG; Guan WANG; Yao LIU; Lu FENG; Meng WANG; Jie LIU; Yi CHEN; Liang OUYANG.

Acta Pharmaceutica Sinica B ; (6): 355-372, 2021.

Article in English | WPRIM | ID: wpr-881141

ABSTRACT

ABSTRACT

Tropomyosin receptor kinase A, B and C (TRKA, TRKB and TRKC), which are well-known members of the cell surface receptor tyrosine kinase (RTK) family, are encoded by the neurotrophic receptor tyrosine kinase 1, 2 and 3 (

AFAP1, actin filament-associated protein 1; AML, acute myeloid leukemia; ARHGEF2, Rho/Rac guanine nucleotide exchange factor 2; BCAN, brevican; BDNF, brain-derived neurotrophic factor

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Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Acta Pharmaceutica Sinica B Year: 2021 Type: Article