Genome mining combined metabolic shunting and OSMAC strategy of an endophytic fungus leads to the production of diverse natural products

Qian WEI; Jian BAI; Daojiang YAN; Xiuqi BAO; Wenting LI; Bingyu LIU; Dan ZHANG; Xiangbing QI; Dequan YU; Youcai HU

Qian WEI; Jian BAI; Daojiang YAN; Xiuqi BAO; Wenting LI; Bingyu LIU; Dan ZHANG; Xiangbing QI; Dequan YU; Youcai HU.

Acta Pharmaceutica Sinica B ; (6): 572-587, 2021.

Article in English | WPRIM | ID: wpr-881155

ABSTRACT

ABSTRACT

Endophytic fungi are promising producers of bioactive small molecules. Bioinformatic analysis of the genome of an endophytic fungus

Azaphilones; Endophytic fungi; Genome mining; Metabolic shunting; Penicillium dangeardii; Silent gene cluster; Trimers

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Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Acta Pharmaceutica Sinica B Year: 2021 Type: Article