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Association between sleep with C reactive protein and insulin metabolism in adolescents / 中国学校卫生
Chinese Journal of School Health ; (12): 819-822, 2021.
Article in Chinese | WPRIM | ID: wpr-881264
ABSTRACT
Objective@#To explore the relationship of sleep with C reactive protein (CRP) abnormality and hyperinsulinemia in adolescents, and to provide reference for early prevention of metabolic disorders.@*Methods@#Based on the Chinese Metabolic Syndrome Cohort Study in Anhui Province, a total of 653 adolescents aged 12 to 19 were selected to examine the relationship between wakeup time, bedtime, sleep disordered breathing (SDB) and CRP abnormality as well as hyperinsulinemia.@*Results@#Later wakeup time (OR=1.68, 95%CI=1.03-2.75) was positively correlated with a higher risk of fasting hyperinsulinemia. Late bedtime (OR=1.96, 95%CI=1.29-2.99) was associated with 2 h postprandial hyperinsulinemia. Among those with high CRP concentration, late wakeup time and late bedtime were positely associated with hyperinsulinemia than those with normal CRP concentration; and the correlation between SDB and hyperinsulinemia was observed.@*Conclusion@#Later wakeup and late bedtime may be risk factors for hyperinsulinemia in adolescents. High concentrations of CRP may further increase the risk of hyperinsulinemia, a condition associated with sleep problems.Teenagers should get up and go to bed as early as possible.

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Index: WPRIM (Western Pacific) Type of study: Observational study / Risk factors Language: Chinese Journal: Chinese Journal of School Health Year: 2021 Type: Article

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Index: WPRIM (Western Pacific) Type of study: Observational study / Risk factors Language: Chinese Journal: Chinese Journal of School Health Year: 2021 Type: Article