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CD4 + T cell differentiation in rheumatoid arthritis / 国际儿科学杂志
International Journal of Pediatrics ; (6): 132-136, 2021.
Article in Chinese | WPRIM | ID: wpr-882312
ABSTRACT
The dysfunction of T cells, especially the interaction of antigen presenting cells and CD4 + T cells, leads to abnormal activation of CD4 + T cells and the initiation of adaptive immune response.Dysfunction of the immune system plays an important role in the pathogenesis of rheumatoid arthritis.It is always considered as the central link of synovial continuous inflammation, articular cartilage and bone destruction in rheumatoid arthritis patients.Exploring CD4 + T cell differentiation and cell subsets provides a new perspective for understanding of arthritis and helps to identify new drug targets.
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Pediatrics Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Pediatrics Year: 2021 Type: Article