Progress in the study of transient hypothyroidism in neonates / 国际儿科学杂志

ABSTRACT

With the nationwide popularization of neonatal heel blood screening, and the change of screening standards and the improvement of premature infant survival rate, the incidence of congenital hypothyroidism in newborns has been increasing year by year.Some of these children need to take medication for all lifetime to maintain normal thyroid function, this is called persistent congenital hypothyroidism, while others don′t, is called transient congenital hypothyroidism.Causes of transient hypothyroidism include iodine deficiency, maternal thyrotrophin receptor blocker antibodies, maternal antithyroid medication, maternal or neonatal iodine exposure, premature delivery, and neonatal hepatic hemangioma.In this review, the author describes the etiology and management of children with transient hypothyroidism, meanwhile summarize several predictors of transient hypothyroidism.