Clinical Outcome of Parosteal Osteosarcoma / 대한골관절종양학회지
The Journal of the Korean Bone and Joint Tumor Society
;
: 20-27, 2013.
Article
in English
| WPRIM
| ID: wpr-88310
ABSTRACT
PURPOSE:
The purpose of this study was to evaluate the oncologic outcomes of parosteal osteosarcoma (POS) and to ascertain the fates of patients after local recurrence (LR). MATERIALS ANDMETHODS:
The authors retrospectively reviewed 22 POS patients with an average follow-up of 114 months (range 36-235 months). Seven of the 22 patients were referred after LR. There were 17 Stage IB and 5 Stage IIB (G2, 2; dedifferentiation, 3). Tumors were located in the femur (11) and in other locations (11). Initial surgical margins were wide in 10, marginal in 5, and intralesional in 7. Correlations between clinico-pathologic variables and LR and clinical courses after LR were evaluated.RESULTS:
The 10-year overall survival rate was 85.7%. Three (14%) patients developed distant metastasis and all of them succumbed to the disease. Nine (41%) patients developed LR. Tumor location, resection type, and surgical margin were found to be correlated with LR. At final follow-up, 7 of the 9 patients that experienced local failure achieved no evidence of disease.CONCLUSION:
A substantial risk of misdiagnosis exists, especially for POS in other than a femoral location. Recurrent tumor re-excision is possible in most cases; however, patients with an aggressive recurrence pattern deserve special attention.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Osteosarcoma
/
Survival Rate
/
Retrospective Studies
/
Follow-Up Studies
/
Diagnostic Errors
/
Femur
/
Neoplasm Metastasis
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
The Journal of the Korean Bone and Joint Tumor Society
Year:
2013
Type:
Article
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