Hyperhomocysteinemia, a Biochemical Tool for Differentiating Ischemic and Nonischemic Central Retinal Vein Occlusion during the Early Acute Phase
Korean Journal of Ophthalmology
;
: 86-91, 2015.
Article
in English
| WPRIM
| ID: wpr-88447
ABSTRACT
PURPOSE:
The purpose of the study was to differentiate ischemic central retinal vein occlusion (CRVO) from nonischemic CRVO during the early acute phase using plasma homocysteine as a biochemical marker.METHODS:
Fasting plasma homocysteine, serum vitamin B12, and folate levels were measured in 108 consecutive unilateral elderly adult (age >50 years) ischemic CRVO patients in the absence of local and systemic disease and compared with a total of 144 age and sex matched nonischemic CRVO patients and 120 age and sex matched healthy control subjects.RESULTS:
Homocysteine level was significantly increased in the patients with ischemic CRVO in comparison with nonischemic CRVO patients (p = 0.009) and also in comparison with control subjects (p 0.1).CONCLUSIONS:
Hyperhomocysteinemia can be regarded as useful in differentiating nonischemic and ischemic CRVO during the early acute phase in absence of local and systemic disease in the elderly adult (age >50 years) population.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Time Factors
/
Retinal Vein Occlusion
/
Biomarkers
/
Case-Control Studies
/
Acute Disease
/
Prospective Studies
/
Follow-Up Studies
/
Hyperhomocysteinemia
/
Diagnosis, Differential
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS