Your browser doesn't support javascript.
loading
Assessment of platelet function using a Platelet Function Analyzer-100 for metabolic syndrome patients / 中华健康管理学杂志
Chinese Journal of Health Management ; (6): 163-166, 2021.
Article in Chinese | WPRIM | ID: wpr-884823
ABSTRACT

Objective:

Metabolic syndrome (MS) patients and determine factors related to platelet hyperactivation.

Methods:

A total of 999 participants (822 males and 177 females) were enrolled. Participants were divided into two groups according to the metabolic index MS group (501) and normal control (NC) group (498). Platelet function was tested with PFA100 (Siemens USA, Deerfield, Illinois) which measures the time it takes for blood to occlude an aperture (closure time, CT) following stimulation with collagen and adenosine diphosphate. Statistical analyses were performed using the SPSS statistical software package, version 22.0 (IBM Corporation, Armonk, NY, USA).

Results:

MS group had significantly shorter CT values compared with NC group (106.6±27.8s) vs (113.7±27.9s). Higher BMI, WC, BP, TC, TG, LDL-C, UA, and PRL were correlated with shorter CT values (all P<0.05).

Conclusion:

Our results indicated platelet hyperactivation exists in MS which was related to obesity and elevated blood pressure, blood lipids, uric acid, and PLR.
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Health Management Year: 2021 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Health Management Year: 2021 Type: Article