Research progress on Parkinson's disease combined with osteoporosis / 中华老年医学杂志

ABSTRACT

Parkinson's disease(PD)is a chronic neurodegenerative disease and commonly seen in middle-aged and elderly people.Combined with age-related loss of bone mass, inadequate intake of vitamin D and calcium due to dysphagia and reduced gastrointestinal motility in the late stages of the disease makes PD patients more susceptible to osteoporosis(OP). Some drugs used to treat PD can also induce and even aggravate osteoporosis in PD patients.Moreover, osteoporosis further impairs mobility in PD patients, causing pain and even fractures.This article reviews the risk factors, pathogenesis, prevention and treatment of PD combined with osteoporosis.