Options of the diagnosis and treatment according to evidence-based patients with prostate carcinoma / 中华泌尿外科杂志

ABSTRACT

Prostate cancer (PC) is the most common malignancy in elderly men. While the majority of PC keeps an indolent biological behavior and progresses slowly, quite a few progresses very fast with poor prognosis. Urologists should take into account of patients′age, general health status and tumor pathology to make an appropriate strategy for PC clinical management. Prostate specific antigen (PSA), digital rectal examination (DRE), magnetic resonance imaging (MRI) of prostate and prostate biopsy are main tools for PC diagnosis. However, appropriate application of all kinds of diagnostic tests to prevent overdiagnosis and overtesting cannot be overemphasized, because methodological defects objectively exist. DRE is a basic examination which is able to provide valuable information for diagnosis. There are multiple therapeutic options for PC with generally similar efficacy and individual shortcoming, which stresses the importance of patients’ consents and choices. Managements of severe complications of advanced PC is critical for improving patients’ life quality.