Series interpretation to Chinese Expert Consensus on the Diagnosis and Treatment of Acromegaly(2020)(Part 2): Early screening and diagnosis of acromegaly / 中华内分泌代谢杂志

ABSTRACT

Acromegaly is usually caused by excessive secretion of growth hormone(GH) for a prolonged period from a pituitary adenoma along with increased levels of insulin-like growth factor-1(IGF-1), which leads to acral and soft tissue enlargement and metabolic dysfunction, such as cardiovascular system or glucose metabolism. Its features are elevated plasma GH/IGF-1 concentrations, however the biochemical tests remain challenging.