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Methicillin-Resistant Staphylococcus aureus (MRSA) Colonization, Risk Factors, and Antibiotic Susceptibility Profile Among Asymptomatic Diabetes Mellitus Type 2 Patients
Philippine Journal of Internal Medicine ; : 58-64, 2020.
Article in English | WPRIM | ID: wpr-886658
ABSTRACT
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BACKGROUND:

Methicillin-resistant Staphylococcus aureus (MRSA) related infections are increased in patients with Diabetes Mellitus and are associated with increased morbidity and mortality.

OBJECTIVES:

This study aims to determine the prevalence, risk factors, and antimicrobial susceptibility patterns of MRSA nasal colonization among individuals with diabetes mellitus.

METHODOLOGY:

This is a prospective cross-sectional study that included adult Filipino patients with diabetes mellitus type 2. Nasal swab samples were analyzed for the presence of MRSA.

RESULTS:

MRSA nasal colonization has a prevalence rate of 6.8% which was associated with a history of antibiotic use. The isolates exhibited resistance to Benzypenicillin/Oxacillin (100%), Clindamycin (42.9%), Vancomycin, and Trimethoprim/Sulfamethoxazole (14.3%).

CONCLUSION:

The prevalence of MRSA in this population is higher compared with other Asian countries. No diabetic-related risk factors were identified to be associated with MRSA nasal colonization. The presence of resistance to most commonly used antibiotics should prompt clinicians appropriately treat infections caused by this organism.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Carrier State / Diabetes Mellitus, Type 2 / Methicillin-Resistant Staphylococcus aureus / Nasal Mucosa Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: English Journal: Philippine Journal of Internal Medicine Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Carrier State / Diabetes Mellitus, Type 2 / Methicillin-Resistant Staphylococcus aureus / Nasal Mucosa Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: English Journal: Philippine Journal of Internal Medicine Year: 2020 Type: Article