Melanoma in Singapore: A 20-year review of disease and treatment outcomes
Annals of the Academy of Medicine, Singapore
;
: 456-466, 2021.
Article
in English
| WPRIM
| ID: wpr-887513
ABSTRACT
INTRODUCTION@#Melanomas in Asians have different clinicopathological characteristics and prognosis from melanomas in Caucasians. This study reviewed the epidemiology and treatment outcomes of cutaneous melanoma diagnosed at a tertiary referral dermatology centre in Singapore, which has a multiracial population. The study also determined whether Asians had comparable relapse-free and overall survival periods to Caucasians in Singapore.@*METHOD@#This is a retrospective review of cutaneous melanoma cases in our centre between 1996 and 2015.@*RESULTS@#Sixty-two cases of melanoma were diagnosed in 61 patients 72.6% occurred in Chinese, 19.4% in Caucasians and 3.2% in Indians, with an over-representation of Caucasians. Superficial spreading melanoma, acral lentiginous melanoma and nodular melanoma comprised 37.1%, 35.5% and 22.6% of the cases, respectively. The median time interval to diagnosis was longer in Asians than Caucasians; median Breslow's thickness in Asians were significantly thicker than in Caucasians (2.6mm versus 0.9mm, @*CONCLUSION@#More physician and patient education on skin cancer awareness is needed in our Asian-predominant population for better outcomes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Singapore
/
Skin Neoplasms
/
Retrospective Studies
/
Treatment Outcome
/
Melanoma
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Annals of the Academy of Medicine, Singapore
Year:
2021
Type:
Article
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