Curve evolution during bracing in children with scoliosis secondary to early-onset neurofibromatosis type 1: indicators of rapid curve progression / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 1983-1987, 2021.
Article
in English
| WPRIM
| ID: wpr-887638
ABSTRACT
BACKGROUND@#Scoliosis secondary to neurofibromatosis type 1 (NF1) in children aged 10°/year) were identified. The age at modulation and the AV before and after modulation were obtained. Patients with (n = 18) and without rapid curve progression (n = 10) were statistically compared.@*RESULTS@#Twenty-eight patients with a mean age of 6.5 ± 1.9 years at the initial visit were reviewed. The mean Cobb angle of the main curve was 41.7° ± 2.4° at the initial visit and increased to 67.1° ± 8.6° during a mean follow-up of 44.1 ± 8.5 months. The overall AV was 6.6° ± 2.4°/year for all patients. At the last follow-up, all patients presented curve progression of >5°, and 20 (71%) patients had progressed by >20°. Rapid curve progression was observed in 18 (64%) patients and was associated with younger age at the initial visit and a higher incidence of modulation change during follow-up (t = 2.868, P = 0.008 and 10°/year is associated with younger age at the initial visit, and modulation change indicated the occurrence of the rapid curve progression phase.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Scoliosis
/
Braces
/
Retrospective Studies
/
Treatment Outcome
/
Neurofibromatosis 1
/
Disease Progression
Type of study:
Observational study
Limits:
Child
/
Child, preschool
/
Humans
Language:
English
Journal:
Chinese Medical Journal
Year:
2021
Type:
Article
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