Complex structures and diverse functions of nuclear bodies: a review / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 2223-2231, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-887791
ABSTRACT
Nuclear bodies are membrane-free nuclear substructures that are localized in the mammalian nuclear matrix region. They are multiprotein complexes that recruit other proteins to participate in various cellular activities, such as transcription, RNA splicing, epigenetic regulation, tumorigenesis and antiviral defense. It is of great significance to clarify the functions and regulatory mechanisms of nuclear bodies to probe related diseases and virus-host interactions. This review takes several nuclear bodies associated proteins as examples, summarizes the formation process, structure and functions of nuclear bodies, and focuses on their important roles in antiviral infection. It is expected to provide new insight into host antiviral mechanisms.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Nuclear Proteins
/
Cell Nucleus
/
Intranuclear Inclusion Bodies
/
Epigenesis, Genetic
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2021
Type:
Article
Similar
MEDLINE
...
LILACS
LIS