Research Progress of FAM60A in the Regulation of Cellular Function / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 469-474, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-887881
ABSTRACT
FAM60A,a cell cycle protein,is a subunit of the SIN3 transcription regulator family member A/histone deacetylase(SIN3-HDAC)complex and plays an important role in cell cycle regulation,cell morphology change,cell proliferation,differentiation and migration,early embryogenesis and so on.Studies in recent years have shown that FAM60A plays a role in the occurrence and development of tumors including human osteosarcoma,esophageal cancer,gastric cancer,lung cancer and liver cancer,providing a new research direction for tumor diagnosis and treatment.Based on the research results in recent years at home and abroad,this paper discussed the effects of FAM60A on cellular functions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cell Differentiation
/
Cell Cycle Proteins
/
Cell Proliferation
/
DNA-Binding Proteins
/
Sin3 Histone Deacetylase and Corepressor Complex
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2021
Type:
Article
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