Advances of Akkermansia muciniphila in regulating host functions / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2760-2765, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-887947
ABSTRACT
Akkermansia muciniphila, abbreviated as AKK and found in 2004, is an oval-shaped gram-negative bacterium isolated from a human feal. A. muciniphila is widely present in the intestinal tract of human. Its specialization in mucin degradation makes it a key organism at the mucosal interface between the lumen and host cells. More and more studies have shown that it can play the role of probiotics. Notably, declined levels of A. muciniphila have been observed in patients with diabetes, liver disease, cardiovascular disease, inflammatory bowel disease, neurodegenerative diseases, etc. In addition, A. muciniphila combined with traditional Chinese medicine, exhibited higher effect on regulating host functions, but the underlying mechanism was still unclear, requiring further in-depth research. Therefore, the aims of this review are to summarize the main effects of A. muciniphila on host health and its relationship with traditional Chinese medicine, summarize the main problems, and provide a reference for the further research of A. muciniphila and traditional Chinese medicine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Inflammatory Bowel Diseases
/
Probiotics
/
Verrucomicrobia
/
Akkermansia
/
Intestines
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2021
Type:
Article
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