Anti-CD19 CART (C-CAR011) Therapy for Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1141-1147, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-888530
ABSTRACT
OBJECTIVE@#To evaluate the safety and efficacy of C-CAR011 in the treatment of relapsed or refractory B-cell non-Hodgkin lymphoma (R/R B-NHL) patients.@*METHODS@#B-NHL patients treated with C-CAR011 infusion following lympho-depletion were enrolled. All the patients were followed up for 1 year after C-CAR011 treatment(5.0×10@*RESULTS@#The ratio of the male and female of 6 patients was 1∶1, and the patients were treated with C-CAR011 at a dose of 5.0×10@*CONCLUSION@#C-CAR011 is a safe treatment option for R/R B-NHL; some patients could achieve long-term sustained responses after C-CAR011 infusion(ClinicalTiral.gov number, NCT03483688).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
B-Lymphocytes
/
Antineoplastic Combined Chemotherapy Protocols
/
Lymphoma, Follicular
/
Lymphoma, Large B-Cell, Diffuse
/
Treatment Outcome
/
Antigens, CD19
/
Neoplasm Recurrence, Local
Limits:
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2021
Type:
Article
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