Differential Diagnosis of Three Commonest Deletion β-Thalassemia in Chinese / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1247-1250, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-888546
ABSTRACT
OBJECTIVE@#To analyze the hematological characteristics of Chinese @*METHODS@#Hemoglobin electrophoresis and blood routine test were used to analyze the hematological indexes of all peripheral blood samples,PCR-Flow fluorescent hybridization and Gap-PCR were used to detect the globin gene mutations and the data were analyzed statistically.@*RESULTS@#The 3 types of deletion β- Thalassemia patients were showed as hypochromic small cell anemia. The MCH and MCV values of Taiwan type β-thalassemia patients were the lowest. The results of hemoglobin electrophoresis showed that the increasing of HbF was found in all of the 3 types. Except for the decreasing of Hb A2 in Chinese @*CONCLUSION@#Through analyze the hematological characteristics, it can be provide that the guidance for the differential diagnosis and genetic consultation of the three commonest deletion β-thalassemia in Chinese.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thalassemia
/
Fetal Hemoglobin
/
China
/
Beta-Thalassemia
/
Diagnosis, Differential
/
Mutation
Type of study:
Diagnostic study
/
Practice guideline
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2021
Type:
Article
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