HIF-1: structure, biology and natural modulators / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 521-527, 2021.
Article
in English
| WPRIM
| ID: wpr-888780
ABSTRACT
Hypoxia-inducible factor 1 (HIF-1), as a main transcriptional regulator of metabolic adaptation to changes in the oxygen environment, participates in many physiological and pathological processes in the body, and is closely related to the pathogenesis of many diseases. This review outlines the mechanisms of HIF-1 activation, its signaling pathways, natural inhibitors, and its roles in diseases. This article can provide new insights in the diagnosis and treatment of human diseases, and recent progress on the development of HIF-1 inhibitors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Signal Transduction
/
Disease
/
Hypoxia-Inducible Factor 1
Limits:
Humans
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2021
Type:
Article
Similar
MEDLINE
...
LILACS
LIS