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New bisabolane-type phenolic sesquiterpenoids from the marine sponge Plakortis simplex / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.) ; (6): 626-631, 2021.
Article in English | WPRIM | ID: wpr-888791
ABSTRACT
Six new bisabolane-type phenolic sesquiterpenoids, including plakordiols A-D (1-4), (7R, 10R)-hydroxycurcudiol (5) and (7R, 10S)-hydroxycurcudiol (6) were isolated from the marine sponge Plakortis simplex collected from the South China Sea. Their structures were determined based on extensive analysis of spectroscopic data. Their configurations were assigned by coupling constant analysis, NOESY correlations, and the modified Mosher's method. Furthermore, their cytotoxic and antibacterial activities were evaluated.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pacific Ocean / Molecular Structure / China / Plakortis / Monocyclic Sesquiterpenes / Anti-Bacterial Agents Limits: Animals Country/Region as subject: Asia Language: English Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pacific Ocean / Molecular Structure / China / Plakortis / Monocyclic Sesquiterpenes / Anti-Bacterial Agents Limits: Animals Country/Region as subject: Asia Language: English Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2021 Type: Article