Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer

ABSTRACT

Ferroptosis is a type of cell death accompanied by iron-dependent lipid peroxidation, thus stimulating ferroptosis may be a potential strategy for treating gastric cancer, therapeutic agents against which are urgently required. Jiyuan oridonin A (JDA) is a natural compound isolated from Jiyuan