Design, synthesis, and biological evaluation of multiple targeting antimalarials
Acta Pharmaceutica Sinica B
;
(6): 2900-2913, 2021.
Article
in English
| WPRIM
| ID: wpr-888893
ABSTRACT
Malaria still threatens global health seriously today. While the current discoveries of antimalarials are almost totally focused on single mode-of-action inhibitors, multi-targeting inhibitors are highly desired to overcome the increasingly serious drug resistance. Here, we performed a structure-based drug design on mitochondrial respiratory chain of
Full text:
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Acta Pharmaceutica Sinica B
Year:
2021
Type:
Article
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