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The Emerging Role of Fast MR Techniques in Traumatic Brain Injury
Investigative Magnetic Resonance Imaging ; : 76-80, 2021.
Article in English | WPRIM | ID: wpr-891135
ABSTRACT
Post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) is a major factor that contributes to the increased socioeconomic burden caused by TBI.Myelin loss has been implicated in the development of PCS following mTBI. Diffusion tensor imaging (DTI), a traditional imaging modality for the evaluation of axonal and myelin integrity in mTBI, has intrinsic limitations, including its lack of specificity and its time-consuming and labor-intensive post-processing analysis. More recently, various fast MR techniques based on multicomponent relaxometry (MCR), including QRAPMASTER, mcDESPOT, and MDME sequences, have been developed. These MCRbased sequences can provide myelin water fraction/myelin volume fraction, a quantitative parameter more specific to myelin, which might serve as a surrogate marker of myelin volume, in a clinically feasible time. In this review, we summarize the clinical application of the MCR-based fast MR techniques in mTBI patients.
Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Investigative Magnetic Resonance Imaging Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Investigative Magnetic Resonance Imaging Year: 2021 Type: Article