Multifocal Electroretinogram Findings after Intravitreal Bevacizumab Injection in Choroidal Neovascularization of Age-Related Macular Degeneration
Korean Journal of Ophthalmology
;
: 161-165, 2011.
Article
in English
| WPRIM
| ID: wpr-89171
ABSTRACT
PURPOSE:
To evaluate the changes in multifocal electroretinogram (mfERG) and optical coherence tomography (OCT) after intravitreal bevacizumab injection in the treatment of age-related macular degeneration (AMD).METHODS:
Twenty-one eyes with choroidal neovascularization secondary to AMD were studied before and after intravitreal bevacizumab injection for best corrected visual acuity (BCVA), OCT, and mfERG.RESULTS:
The BCVA improved, while central macular thickness and total macular volume in OCT decreased after intravitreal bevacizumab injection (p = 0.03, 0.01, and 0.01, respectively). In mfERG, the amplitude of P1, and implicit time of P1 and N1 indicated a statistically significant improvement of retinal response after intravitreal bevacizumab injection.CONCLUSIONS:
There is a potential role for mfERG in evaluating the effect on retinal function of intravitreal bevacizumab injection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Retina
/
Visual Acuity
/
Choroidal Neovascularization
/
Angiogenesis Inhibitors
/
Tomography, Optical Coherence
/
Electroretinography
/
Eyeglasses
/
Intravitreal Injections
/
Macular Degeneration
/
Antibodies, Monoclonal
Type of study:
Diagnostic study
Limits:
Adult
/
Aged
/
Humans
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS