Changes in the Eradication Rate of Conventional Triple Therapy for Helicobacter pylori Infection in Korea / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 141-145, 2014.
Article
in Korean
| WPRIM
| ID: wpr-89372
ABSTRACT
Although, the prevalence of Helicobacter pylori infection in Korea has declined owing to the eradication therapy, recent seroprevalence of H. pylori infection is still reported to be as high as 54.4%. Until now, "standard regimen" for eradication of H. pylori has been conventional triple therapy consisting of proton pump inhibitor, amoxicillin, and clarithromycin. However, with the increase in antibiotic resistance, especially against clarithromycin, the eradication rate of conventional triple therapy has steadily declined during the past 13 years in Korea. Present eradication rate of standard triple therapy is reported to be less than 80%, which is the Maginot line of efficacy for the currently available regimen. Therefore, new first line eradication regimen is needed to enhance the eradication rate of H. pylori infection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drug Administration Schedule
/
Helicobacter pylori
/
Helicobacter Infections
/
Clarithromycin
/
Asian People
/
Drug Therapy, Combination
/
Proton Pump Inhibitors
/
Republic of Korea
/
Disease Eradication
/
Amoxicillin
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
The Korean Journal of Gastroenterology
Year:
2014
Type:
Article
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