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Analysis of the Maternal and Perinatal Risk Factors of Infantile Hemangioma in Patients in Neonatal Intensive Care Units / 대한피부과학회지
Korean Journal of Dermatology ; : 332-340, 2021.
Article in English | WPRIM | ID: wpr-894281
ABSTRACT
Background@#Infantile hemangioma (IH) is one of the most common tumors in infants. IH occurs more commonly in premature and low birth weight infants, but only a few studies have analyzed the risk factors for IH in neonatal intensive care units (NICUs) in Korea. @*Objective@#We investigated the risk factors for IH in patients admitted to the NICU at a single institution. @*Methods@#A single-center retrospective case-control study was conducted in 37 patients with hemangioma and 185 matched-control babies who were admitted to the NICU between 2013 and 2020. Odds ratios (ORs) and multivariate conditional logistic regression models were used to determine the associations between IH and the potential risk factors. @*Results@#Of the 1,206 neonates admitted to the NICU, 37 had IH, and the prevalence was 3.1%. IH was most commonly found on the trunk (33.3%), followed by the head and neck (29.4%). After adjustment, the risk factors found to be significantly associated with IH were female sex (OR=3.0, 95% confidence interval [CI]=1.4∼6.8), extreme preterm (OR=6.9, 95% CI=1.3∼38.0), very low birth weight (OR=11.9, 95% CI=2.9∼49.3), low 1-minute Apgar scores of <7 (OR=2.3, 95% CI=1.1∼4.9), and multiple gestation (OR=5.0, 95% CI=1.7∼14.9). @*Conclusion@#This matched case–control study revealed that risk factors such as female sex, extremely preterm birth, very low birth weight, low 1-minute Apgar score, and multiple gestations may affect the occurrence of IH. Therefore, if these risk factors are present, they need to be actively managed at an early stage through close physical examination to prevent complications.
Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: English Journal: Korean Journal of Dermatology Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: English Journal: Korean Journal of Dermatology Year: 2021 Type: Article