A Case of Acute Follicular Graft versus Host Reaction / 대한피부과학회지

ABSTRACT

Acute graft-versus-host disease (GVHD) is a life threatening complication of allogeneic bone marrow transplantation. It is important to recognize the dermatologic manifestations of acute GVHD, as skin is often the initial organ of involvement. The rash typically is a blanchable, erythematous macular eruption. We present a case of acute follicular graft-versus-host reaction (GVHR) characterized by erythematous to violaceous follicular papular eruption clinically and follicular epithelial dyskeratosis histopathologically. Although acute follicular GVHR is rare, it is important to recognize it as an early skin manifestation of acute cutaneous GVHR allowing prompt therapy.