Unveiling the Functions of the VosA-VelB Target Gene vidD inAspergillus nidulans
Mycobiology
;
: 258-266, 2021.
Article
in English
| WPRIM
| ID: wpr-895049
ABSTRACT
The velvet regulators VosA and VelB are primarily involved in spore maturation and dormancy. Previous studies found that the VosA-VelB hetero-complex coordinates certain target genes that are related to fungal differentiation and conidial maturation in Aspergillus nidulans. Here, we characterized the VosA/VelB-inhibited developmental gene vidD in A. nidulans.Phenotypic analyses demonstrated that the vidD deleted mutant exhibited defect fungal growth, a reduced number of conidia, and delayed formation of sexual fruiting bodies. The deletion of vidD decreased the amount of conidial trehalose, increased the sensitivity against heat stress, and reduced the conidial viability. Moreover, the absence of vidDresulted in increased production of sterigmatocystin. Together, these results show that vidD is required for proper fungal growth, development, and sterigmatocystin production in A. nidulans.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Mycobiology
Year:
2021
Type:
Article
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