Multiple endocrine neoplasia type 1 with anterior mediastinal parathyroid adenoma: successful localization using Tc-99m sestamibi SPECT/CT
Annals of Surgical Treatment and Research
;
: 323-326, 2016.
Article
in English
| WPRIM
| ID: wpr-89523
ABSTRACT
The most common manifestation of multiple endocrine neoplasia type 1 (MEN1) is hyperparathyroidism. Treatment of hyperparathyroidism in MEN patients is surgical removal of the parathyroid glands, however ectopic parathyroid gland is challenging for treatment. A 51-year-old female, the eldest of 3 MEN1 sisters, had hyperparathyroidism with ectopic parathyroid adenoma in the mediastinal para-aortic region, which was detected by technetium-99m (Tc-99m) sestamibi scintigraphy and single-photon emission computed tomography/computed tomography (SPECT/CT). She underwent total parathyroidectomy with video-assisted thoracoscopic surgery on an anterior mediastinal mass. Anterior mediastinal parathyroid adenoma in MEN1 patients is rare. Precise localization of an ectopic parathyroid gland with Tc-99m sestamibi SPECT/CT can lead to successful treatment of hyperparathyroidism. This is the first reported case in the literature of mediastinal parathyroid adenoma in MEN1 patient visualized by Tc-99m sestamibi SPECT/CT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parathyroid Neoplasms
/
Parathyroid Glands
/
Multiple Endocrine Neoplasia
/
Radionuclide Imaging
/
Tomography, Emission-Computed, Single-Photon
/
Parathyroidectomy
/
Multiple Endocrine Neoplasia Type 1
/
Thoracic Surgery, Video-Assisted
/
Siblings
/
Hyperparathyroidism
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2016
Type:
Article
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