Seven Steps to the Diagnosis of NSAIDs Hypersensitivity: How to Apply a New Classification in Real Practice?
Allergy, Asthma & Immunology Research
;
: 312-320, 2015.
Article
in English
| WPRIM
| ID: wpr-89610
ABSTRACT
Frequent use of non-steroidal anti-inflammatory drugs (NSAIDs) has been paralleled by increasing occurrence of adverse reactions, which vary from mild local skin rashes or gastric irritation to severe, generalized symptoms and even life-threatening anaphylaxis. NSAID-induced hypersensitivity reactions may involve both immunological and non-immunological mechanisms and should be differentiated from type A adverse reactions. Clinical diagnosis and effective management of a hypersensitive patient cannot be achieved without identifying the underlying mechanism. In this review, we discuss the current classification of NSAID-induced adverse reactions and propose a practical diagnostic algorithm that involves 7 steps leading to the determination of the type of NSAID-induced hypersensitivity and allows for proper patient management.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anti-Inflammatory Agents, Non-Steroidal
/
Aspirin
/
Classification
/
Diagnosis
/
Drug Hypersensitivity
/
Exanthema
/
Hypersensitivity
/
Anaphylaxis
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Allergy, Asthma & Immunology Research
Year:
2015
Type:
Article
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