Long-Term Survival in Stage IV Esophageal Adenocarcinoma with Chemoradiation and Serial Endoscopic Cryoablation
Clinical Endoscopy
;
: 491-494, 2017.
Article
in English
| WPRIM
| ID: wpr-89710
ABSTRACT
Esophageal cancer has a poor overall prognosis and is frequently diagnosed at a late stage. Conventional treatment for metastatic esophageal cancer involves chemotherapy and radiation. Local disease control plays a significant role in improving survival. Endoscopic spray cryotherapy is a novel modality that involves freezing and thawing to produce local ablation of malignant tissue via ischemic mechanisms. Spray cryotherapy has been shown to be effective, particularly for early T-stage, superficial esophageal adenocarcinomas. We present the case of a 72-year-old-male with locally recurrent stage IV esophageal adenocarcinoma and long-term survival of 7 years to date, with concurrent chemoradiation and serial cryoablation. He remains asymptomatic and continues to undergo chemotherapy and sequential cryoablation. The findings highlight the long-term safety and efficacy of cryotherapy in combination with chemoradiation, and suggest that cryoablation may have an additive role in the treatment of advanced stage esophageal adenocarcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Esophageal Neoplasms
/
Adenocarcinoma
/
Cryotherapy
/
Cryosurgery
/
Drug Therapy
/
Freezing
Type of study:
Prognostic study
Language:
English
Journal:
Clinical Endoscopy
Year:
2017
Type:
Article
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