The Outcome of Fungal Pneumonia with Hematological Cancer / 감염과화학요법
Infection and Chemotherapy
;
: 530-538, 2020.
Article
in English
| WPRIM
| ID: wpr-898588
ABSTRACT
Background@#Fungal pneumonia is a common infectious complication of hematological cancer (HC) patients. In this retrospective study, the objective was set to identify the risk factors and outcome of fungal pneumonia in adult HC patients. @*Materials and Methods@#This retrospective study was conducted with adult (>16 years) HC patients from January 2017 and December 2018. @*Results@#During the study period, of 181 patients included 76 were diagnosed with fungal pneumonia. The most common HC was identified as acute myeloid leukaemia (40%). Of the participating patients, 52 (29%) were hematopoietic stem cell transplant (HSCT) recipients.The median age of patients with fungal pneumonia was significantly greater 57 vs. 48 (odds ratio [OR] 1.08) and they had longer hospitalization durations (OR 1.14). Overall, 37 patients (20%) died, and 28-day mortality was significantly greater among patients with fungal pneumonia than without fungal pneumonia (33% vs. 11%). The most significant risk factors for mortality in fungal pneumonia were identified as need of intensive care unit (ICU) (OR 191.2, P <0.001) and the need of vasopressor support (OR81.6, P <0.012). ICU-mortality was (88%). @*Conclusion@#Fungal pneumonia is a lethal complication in HC patients. Intensive care need is the most important predictive factor for mortality.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
Infection and Chemotherapy
Year:
2020
Type:
Article
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