Clinically Significant Monocyte Biomarker for Differential Diagnosis of COVID-19 Pneumonia in the Emergency Department / 계명의대학술지
Keimyung Medical Journal
;
: 26-31, 2021.
Article
in English
| WPRIM
| ID: wpr-901494
ABSTRACT
Objectives@#To determine basic patient characteristics and biomarkers to help in the early diagnosis of Coronavirus disease 2019 (COVID-19) pneumonia in patients with pneumonia who visited the emergency department (ED). @*Methods@#This retrospective study evaluated patients diagnosed with community-acquired pneumonia (CAP) or COVID-19 pneumonia in ED at four tertiary medical centers between February 1 and March 31, 2020. Parameters related to the differential diagnosis between CAP and COVID-19 were investigated. Clinical characteristics and laboratory results of biomarkers were analyzed. @*Results@#In total, 81 patients presented to the ED with COVID-19 pneumonia. Multivariate logistic regression analysis showed that monocyte count [odds ratio (OR) 0.996; 95% confidence interval (CI) 0.994–0.999] and pneumonia severity index (PSI) [OR 1.025; 95% CI 1.002–1.049] were associated with diagnosis of COVID-19 pneumonia. The area under the curve comprising the combination of monocyte and PSI was 0.789. @*Conclusion@#Differential diagnosis of COVID-19 pneumonia from pneumonia patients who visited the emergency room can be made by monocyte count and PSI score.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Screening study
Language:
English
Journal:
Keimyung Medical Journal
Year:
2021
Type:
Article
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