Melixyloidin, A New Acridone Alkaloid from Melicope xanthoxyloides Leaves
Natural Product Sciences
;
: 183-186, 2021.
Article
in English
| WPRIM
| ID: wpr-902796
ABSTRACT
A new acridone alkaloid, melixyloidin (1), and two known alkaloids (2-3) were isolated from Melicope xanthoxyloides (F. Muell) T.G. Hartley leaves. The structure of melixyloidin were elucidated using NMR spectra and high-resolution ESIMS data. Acridone alkaloids 1-3 were evaluated against MCF-7 and HeLacells. 1,3,4-Trimethoxy-10-methylacridin-9-one (2) showed potent cytotoxic activity against MCF-7 cells with an IC50 value of 5.31 μM.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Natural Product Sciences
Year:
2021
Type:
Article
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