The Role of MicroRNA in Force-Related Periodontal Inflammatory Response and Tissue Remodeling / 医用生物力学
Journal of Medical Biomechanics
;
(6): E164-E168, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-904381
ABSTRACT
Micro-ribonucleic acid(miRNA) is a kind of non-coding single-stranded RNA, which can regulate the expression of genetic information by inhibiting mRNA translation of the target gene and participate in the occurrence and development of a variety of biological processes in vivo. miRNAs also take part in inflammatory diseases and tissue remodeling induced by mechanical forces. Mechanosensitive cells in periodontal tissue can lead to pathological/physiological changes such as periodontal inflammatory response and periodontal remodeling. miRNAs might have played important roles in the occurrence and development of force-related periodontal inflammatory diseases and tissue remodeling, by inhibiting the translation of specific genes in these cells. This article reviews the roles of miRNAs in force-related inflammatory response and tissue remodeling, especially in periodontal inflammatory response and tissue remodeling.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Biomechanics
Year:
2021
Type:
Article
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