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The Characteristics of Salivary alpha-Amylase Reactivity to Negative Affective Stimuli / 신경정신의학
Journal of Korean Neuropsychiatric Association ; : 441-449, 2008.
Article in Korean | WPRIM | ID: wpr-90588
ABSTRACT

OBJECTIVES:

The aim of this study is to understand the characteristics of salivary ALPHA-amylase reactivity (sAA), as a biological maker of stress, by viewing negative affective pictures.

METHODS:

Forty six normal healthy subjects participated in this study. Prior to the experiment, the participants completed baseline psychological assessment including trait-dependent anxiety scales. On experiment, saliva samples were collected one time before and three times after exposure to 5-min stressor consisting 20 negative affective pictures. The state-related scales were measured before and just after exposure to stressor to assess the subjects' state anxiety.

RESULTS:

Overall, sAA was significantly decreased over time with the increase of negative affect score and state-anxiety. The Anxiety Scale Inventory scores were negatively correlated with the baseline as well as the other following sAA levels (all ps or =2, N=19) than in the lower counterpart (<2, N=27) in comparison between them (mean46.6 vs. 76.5 U/mL, p=.024). After the exposure, the means of sAA levels significantly decreased over time in the lower susceptible group, whereas did not in the higher one (mean-1.7 vs. -23.0 U/mL, p=.031).

CONCLUSION:

These findings suggest that the baseline level of sAA and its reactivity depend on individual trait of anxiety as well as state of reactivity to affective stress.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Anxiety / Saliva / Weights and Measures / Biomarkers / Alpha-Amylases Language: Korean Journal: Journal of Korean Neuropsychiatric Association Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Anxiety / Saliva / Weights and Measures / Biomarkers / Alpha-Amylases Language: Korean Journal: Journal of Korean Neuropsychiatric Association Year: 2008 Type: Article