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Clinical Evidence and Theory of COVID-19 by Traditional Chinese Medicine / 中国实验方剂学杂志
Chinese Journal of Experimental Traditional Medical Formulae ; (24): 191-197, 2021.
Article in Chinese | WPRIM | ID: wpr-906286
This study aims to investigate the etiology, pathogenic properties and pathogenic characteristics of corona virus disease-2019 (COVID-19) in traditional Chinese medicine(TCM), so as to provide ideas for clinical treatment based on syndrome differentiation. Efforts were made to retrive relevant literature concerning clinical studies, theoretical discussions and TCM diagnosis and treatment schemes issued by the state and various provinces, municipalities, autonomous regions and municipalities directly under the central government in relation to TCM from China Knowledge Network(CNKI) and Wanfang Database, and to analyze and summarize the etiologypathology, theoretical viewpoints, clinical symptoms and signssyndrome differentiation and medication rules. Currently, the common understanding of the etiology of COVID-19 in the field of TCM is the infection of "pestilential pathogen". However, there is a dispute over cold and heat or mixed understanding of cold and heat in terms of pathogenic attributes. The pathogenic factors are different from each other in dampness, toxin, drynessfireheat), wind, filth, depression, etc. There are various understandings on the pathogenesis including dampness, coldheat, toxin, stasis, phlegm, stagnation, knot, dryness, filth, deficiency, blocking, collapse and asthma, etc. The etiology and pathogenesis are often mixed up. Integration of cold and heatdryness and dampness, and other contradictory pathogens or pathogenesis is widely seen, which lacks the logicality of theoretical systems, and does not in line with the thinking characteristics of TCM on the etiologypathogenesis, and syndrome differentiation of exogenous diseases. The main idea of medication in treatment is to diffuse the lung, clear away heat, eliminate dampness, resolve phlegm and repel foulness with aromatics. Maxing Shigantang is used as the core prescription. Chosen warm acrid drugs are mainly the ones with the effect of fragrance, removing dampness, resolving phlegm, and invigorating spleen. They are not the ones with the effects of warming yang and dissipating cold, but the combination of cold and heat, suggesting the complexity of etiology and pathogenesis. COVID-19 is categorized as plaque in TCM, and its etiology is "pestilential pathogen". This pestilential pathogen possesses not only the basic properties of toxin and filth, but also the characteristics of dampness, heat and wind. Throughout the course of the disease, phlegm, stasis, stagnation and other secondary pathogenic factors also occur. The evolution of pathogenesis is characterized by depression, blocking, and deficiency. There are more evidences that the pestilential pathogen of COVID-19 belongs to heat property no matter in the aspects of clinical manifestation, transmission lawsyndrome differentiation at different stages), or in compatibility of medication.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Experimental Traditional Medical Formulae Year: 2021 Type: Article





Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Experimental Traditional Medical Formulae Year: 2021 Type: Article