Evaluation of Renal Oxygenation in Normal Korean Volunteers Using 3.0 T Blood Oxygen Level-Dependent MRI
Journal of the Korean Society of Magnetic Resonance in Medicine
;
: 19-25, 2013.
Article
in English
| WPRIM
| ID: wpr-90665
ABSTRACT
PURPOSE:
Renal blood oxygen level-dependent (BOLD) MRI has been used in the evaluation of renal oxygenation. We tried to provide the normal R2* value of the human kidney with 3.0 T, and evaluated the differences in R2* values according to gender and location. MATERIALS ANDMETHODS:
Twenty-four healthy volunteers underwent BOLD MRI at 3.0 T. Multi gradient echo-echo planar imaging sequence with seventeen echoes was used. After generation of the T2* map, the R2* was calculated. The statistical differences in R2* values between the cortex and medulla, males and females, and the right and left kidney were analyzed. The regional differences of R2* within the both kidneys were evaluated respectively.RESULTS:
BOLD MRI was successful in all participants. No gross artifact interfered with R2* measurement. The mean R2* at 3.0 T was 17.1 +/- 2.60 s-1 in the cortex and 27.7 +/- 4.83 s-1 in the medulla (p < 0.001). The R2* value in the medulla was significantly higher in the male than female volunteers (p = 0.025). There were no statistical differences of R2* according to the side and location in the kidney (p = 0.197).CONCLUSION:
Renal BOLD MRI can be efficiently performed with 3.0 T MRI. Renal medullary hypoxia is present in normal volunteers. Our results may be used as reference values in the evaluation of pathologic conditions using BOLD MRI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Reference Values
/
Artifacts
/
Kidney
/
Hypoxia
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of the Korean Society of Magnetic Resonance in Medicine
Year:
2013
Type:
Article
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